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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH1L
All Species:
30.61
Human Site:
Y2258
Identified Species:
67.33
UniProt:
Q9NR48
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR48
NP_060959.2
2969
332790
Y2258
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Chimpanzee
Pan troglodytes
XP_513861
2964
332149
Y2253
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851926
2974
332800
Y2263
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99MY8
2958
331289
Y2248
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Rat
Rattus norvegicus
NP_001101159
2918
326454
Y2208
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511389
1395
154154
R799
Q
V
F
R
I
S
H
R
S
Y
T
F
Y
H
E
Chicken
Gallus gallus
XP_422858
2954
330578
Y2244
P
A
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692254
2962
327377
Y2203
N
S
G
T
E
L
T
Y
D
Y
N
F
H
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW15
2226
246247
G1630
T
A
S
S
P
A
L
G
T
T
N
G
D
I
P
Honey Bee
Apis mellifera
XP_001122948
2180
246181
R1584
S
K
G
M
C
K
S
R
K
V
G
D
S
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784903
3312
363645
Y2613
Q
P
G
E
E
L
T
Y
D
Y
N
F
H
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.1
N.A.
91.7
91.2
N.A.
21.5
79.9
N.A.
40.9
N.A.
26.1
26
N.A.
27.3
Protein Similarity:
100
99.6
N.A.
97
N.A.
95.3
94.4
N.A.
31.8
89.2
N.A.
53
N.A.
42.2
43.9
N.A.
43.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
100
N.A.
86.6
N.A.
13.3
6.6
N.A.
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
N.A.
93.3
N.A.
20
20
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
64
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
73
0
0
10
10
0
0
% D
% Glu:
0
0
0
10
73
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
82
0
0
73
% F
% Gly:
0
0
82
0
0
0
0
10
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
73
10
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
73
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
82
0
0
10
0
% N
% Pro:
55
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
10
0
10
10
0
10
0
0
0
10
73
0
% S
% Thr:
10
0
0
64
0
0
73
0
10
10
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
82
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _